- August 19, 2015
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Obese Teenagers have high risk of developing Cancer of large Interstine and Rectum
It has been known for sometimes that incidence of several cancers including that of breast, uterus, cervix, esophagus, pancreas, prostrate, kidney and colon are 3-5 times more common in obese people compared to normal weight individuals. It has now come to light that male teenagers who are overweight and obese are more than twice as likely to develop cancer of large intestine and rectum.
In a recent study, it was found that teenagers who had a BMI(Body Mass Index) in upper overweight category (BMI: 27.5 to <30 kg/m2) had a 2.08 higher risk of developing cancers of large intestine and rectum compared to teenagers who had a normal weight (BMI:18.5 to <25 kg/m2). Those who were obese (BMI: ≥30 kg/m2) had a 2.38-fold higher risk. Thus teenagers have increased risk of developing the above mentioned cancers with increasing weight and BMI.
As the incidence of childhood and adolescent obesity is increasing, we can expect increased incidences of cancers of colon and rectum in the coming years. The main cause for this may be lack of high fibers in the diet leading to constipation and increased exposure of large intestine and rectum to cancer causing substances. Other factors such as leptin, insulin and steroid hormones may also play a role.